http://medicineworld.org/news/ovariannews.html MedicineWorld.Org brings daily ovarian cancer news from various sources to keep you updated on the latest events in the world on this topic. Medicineworld heart watch news service is the most comprehensive heart watch news service on the internet. We keep an archive of previous few days of news on this site. Please go down through the list to find the older news items. Wed, 10 Mar 2010 14:21:37 GMT en-us http://medicineworld.org/images/ovaries.jpg http://medicineworld.org/news/ovariannews.html 108 87 http://medicineworld.org/stories/lead/3-2010/elective-removal-of-ovaries-during-hysterectomy.html http://medicineworld.org/stories/lead/3-2010/elective-removal-of-ovaries-during-hysterectomy.html Wed, 10 Mar 2010 14:21:37 GMT Removal of the ovaries (bilateral oophorectomy) while performing a hysterectomy is common practice to prevent the subsequent development of ovary cancer. This prophylactic procedure is performed in 55% of all U.S. women having a hysterectomy, or approximately 300,000 times each year. An article in the March/recent issue of The Journal of Minimally Invasive Gynecology suggests that this procedure may do more harm than good........ ]]> http://medicineworld.org/stories/lead/2-2010/fat-tissue-in-women-with-polycystic-ovary-syndrome.html http://medicineworld.org/stories/lead/2-2010/fat-tissue-in-women-with-polycystic-ovary-syndrome.html Wed, 10 Mar 2010 14:21:37 GMT Fat tissue in women with Polycystic Ovary Syndrome produces an inadequate amount of the hormone that regulates how fats and glucose are processed, promoting increased insulin resistance and inflammation, glucose intolerance, and greater risk of diabetes and heart disease, as per a research studyconducted at the Center for Androgen-Related Research and Discovery at Cedars-Sinai Medical Center........ ]]> http://medicineworld.org/stories/lead/7-2009/chemo-directly-to-ovarian-cancer-cells.html http://medicineworld.org/stories/lead/7-2009/chemo-directly-to-ovarian-cancer-cells.html Wed, 10 Mar 2010 14:21:37 GMT With a novel therapeutic delivery system, a research team led by researchers at The University of Texas M. D. Anderson Cancer Center has successfully targeted a protein that is over-expressed in ovary cancer cells. Using the EphA2 protein as a molecular homing mechanism, chemotherapy was delivered in a highly selective manner in preclinical models of ovary cancer, the scientists report in the July 29 issue of the Journal of the National Cancer Institute....... ]]> http://medicineworld.org/stories/lead/4-2009/against-recurrent-gynecologic-cancers.html http://medicineworld.org/stories/lead/4-2009/against-recurrent-gynecologic-cancers.html Wed, 10 Mar 2010 14:21:37 GMT Recurrent and metastatic endometrial and ovary cancers can be notoriously difficult to treat: They have spread to other organs and typically have developed resistance to chemotherapy; and patients already heavily treated with chemotherapy may not be able to endure more chemo. Now, physicians at Albert Einstein College of Medicine of Yeshiva University have shown that a combination of two chemotherapy drugs not only produced clinical benefit for such patients but were also well tolerated. The findings are published online in the journal Gynecologic Oncology....... ]]> http://medicineworld.org/stories/lead/4-2009/ovarian-cancer-screening.html http://medicineworld.org/stories/lead/4-2009/ovarian-cancer-screening.html Wed, 10 Mar 2010 14:21:37 GMT The only available screening tests for ovary cancer fail to catch early signs of the disease and often result in unnecessary surgery, said scientists at the University of Alabama at Birmingham (UAB) Comprehensive Cancer Center. The newly released study looked at a screening regimen that combines ultrasound and a blood test for CA-125, a marker for women's cancer........ ]]> http://medicineworld.org/stories/lead/2-2009/ovarian-cancer-from-fertility-drugs.html http://medicineworld.org/stories/lead/2-2009/ovarian-cancer-from-fertility-drugs.html Wed, 10 Mar 2010 14:21:37 GMT The use of fertility drugs does not increase a woman's risk of developing ovary cancer, finds a large study from Danish scientists published on bmj.com today. During the past three decades there has been considerable debate as to whether use of fertility drugs increases a woman's risk of developing ovary cancer. Prior studies have given conflicting results and concerns remain, especially for women who undergo several cycles of therapy or who never succeed in becoming pregnant........ ]]> http://medicineworld.org/stories/lead/2-2009/genes-associated-with-ovarian-cancer-survival.html http://medicineworld.org/stories/lead/2-2009/genes-associated-with-ovarian-cancer-survival.html Wed, 10 Mar 2010 14:21:37 GMT A newly released study published this week in the open-access journal PLoS Medicine identifies molecular pathways linked to outcomes in ovary cancer. Currently, outcomes following diagnosis of ovary cancer are very poor, with up to 65-70% of women dying within five years of diagnosis. Anne Crijns and her colleagues from the University of Groningen in the Netherlands aimed to find out whether the expression levels of particular genes were linked to overall survival in ovary cancer. The scientists initially studied a series of tissue samples, obtained during surgery to remove malignant tissue from 157 consecutive patients seen at the University Medical Center Groningen. Analysis of the samples identified 86 genes which correlated with overall survival in the women. The scientists were then able to confirm, for 57 of the 86 genes, that these were also correlated with survival in a second, entirely separate dataset. Specific genes, and pathways, were identified which provide specific targets around which scientists might be able to design potential therapies in future........ ]]> http://medicineworld.org/cancer/lead/9-2008/ovarian-cancer-drug-promising-new-treatment.html http://medicineworld.org/cancer/lead/9-2008/ovarian-cancer-drug-promising-new-treatment.html Wed, 10 Mar 2010 14:21:37 GMT Irvine, Calif. Women with recurrent ovary cancer can be helped by an experimental treatment using a drug already touted for its ability to fight other cancers, a finding that provides hope for improved therapy of this deadly disease. Dr. Bradley Monk, a UC Irvine gynecologic oncologist who led the worldwide phase III clinical trial, said trabectedin is the most recent addition to a short list of active drug therapies for recurrent ovary cancer. He presents study results Sept. 15 at the 33rd Congress of the European Society for Medical Oncology in Stockholm........ ]]> http://medicineworld.org/cancer/lead/4-2008/ovarian-cancer-stem-cells-identified.html http://medicineworld.org/cancer/lead/4-2008/ovarian-cancer-stem-cells-identified.html Wed, 10 Mar 2010 14:21:37 GMT Scientists at Yale School of Medicine have identified, characterized and cloned ovary cancer stem cells and have shown that these stem cells may be the source of ovary cancers recurrence and its resistance to chemotherapy. These results bring us closer to more effective and targeted therapy for epithelial ovary cancer, one of the most lethal forms of cancer, said Gil Mor, M.D., associate professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine........ ]]> http://medicineworld.org/cancer/lead/4-2008/death-of-ovarian-cancer-cells.html http://medicineworld.org/cancer/lead/4-2008/death-of-ovarian-cancer-cells.html Wed, 10 Mar 2010 14:21:37 GMT In a discovery that may be useful for maintaining remission in chemo-resistant ovary cancer, Yale researchers report that pre-clinical studies have shown the drug compound NV-128 can induce the death of ovary cancer cells by halting the activation of a protein pathway called mTOR. Gil Mor, M.D., associate professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine, and associate research scientist Ayesha Alvero, M.D. presented the data April 15 during an oral presentation at the annual meeting of the American Association for Cancer Research........ ]]> http://medicineworld.org/cancer/lead/3-2008/ovary-less-responsive-to-chemo.html http://medicineworld.org/cancer/lead/3-2008/ovary-less-responsive-to-chemo.html Wed, 10 Mar 2010 14:21:37 GMT Recurrent low-grade serous carcinoma, a rare type of ovary cancer, is less sensitive to chemotherapy and therefore more difficult to treat than more common high-grade ovary cancers, as per scientists from The University of Texas M. D. Anderson Cancer Center. The findings were reported at the Society of Gynecologic Oncologists 39th Annual Meeting on Women's Cancers........ ]]> http://medicineworld.org/cancer/lead/2-2008/early-stage-ovarian-cancer.html http://medicineworld.org/cancer/lead/2-2008/early-stage-ovarian-cancer.html Wed, 10 Mar 2010 14:21:37 GMT Scientists at Yale School of Medicine have developed a blood test with enough sensitivity and specificity to detect early stage ovary cancer with 99 percent accuracy. Results of this new study are reported in the February 15 issue of the journal Clinical Cancer Research. The results build on work done by the same Yale group in 2005 showing 95 percent effectiveness of a blood test using four proteins........ ]]> http://medicineworld.org/cancer/lead/2-2008/why-certain-ovarian-cancers-develop-resistance.html http://medicineworld.org/cancer/lead/2-2008/why-certain-ovarian-cancers-develop-resistance.html Wed, 10 Mar 2010 14:21:37 GMT A team of scientists led by Fred Hutchinson Cancer Research Center has identified a new mechanism that explains why some recurrent ovarian tumors become resistant to therapy with usually used platinum-based chemotherapy drugs such as cisplatin and carboplatin. They describe their research online Feb. 10 in the journal Nature........ ]]> http://medicineworld.org/cancer/lead/11-2007/predicting-the-future-in-ovarian-cancer.html http://medicineworld.org/cancer/lead/11-2007/predicting-the-future-in-ovarian-cancer.html Wed, 10 Mar 2010 14:21:37 GMT Kisspeptin and its receptor GPR54 predict a favourable clinical outcome in women with ovarian carcinoma, and are specific for the clear cell carcinoma subtype, research published this week in the online open access journal, BMC Medicine, reveals. The kisspeptins, a family of peptide hormones, and the receptor GPR54 have previously been linked to anti-metastatic activity in certain human tumours. In this study, scientists have shown that kisspeptin and GPR54 are independent prognostic biomarkers specific for ovarian clear cell carcinoma - the first such markers to be identified........ ]]> http://medicineworld.org/cancer/lead/10-2007/avastin-improves-ovarian-cancer-treatment.html http://medicineworld.org/cancer/lead/10-2007/avastin-improves-ovarian-cancer-treatment.html Wed, 10 Mar 2010 14:21:37 GMT A new study appearing in International Journal of Gynecological Cancer states that Bevacizumab, a biologic anti-cancer agent that prevents tumor growth by interfering with the formation of new blood vessels, may have the potential to improve the efficacy of standard combination chemotherapy in ovary cancer........ ]]>