MedicineWorld.Org
Your gateway to the world of medicine
Home
News
Cancer News
About Us
Cancer
Health Professionals
Patients and public
Contact Us
Disclaimer

Medicineworld.org: Anti-depressants and cataracts

Back to ophthalmology news Blogs list Cancer blog  


Subscribe To Ophthalmology News RSS Feed  RSS content feed What is RSS feed?

Anti-depressants and cataracts




Some anti-depressant drugs are linked to an increased chance of developing cataracts, as per a new statistical study by scientists at the University of British Columbia, Vancouver Coastal Health Research Institute and McGill University.

The study, based on a database of more than 200,000 Quebec residents aged 65 and older, showed statistical relationships between a diagnosis of cataracts or cataract surgery and the class of drugs called selective serotonin reuptake inhibitors (SSRIs), as well as between cataracts and specific drugs within that class.



Anti-depressants and cataracts

Published online today in the journal Ophthalmology, the study does not prove causation but only reveals an association between the use of SSRIs and the development of cataracts. The study could not account for the possibility of smoking - which is a risk factor for cataracts - and additional population-based studies are needed to confirm these findings, the scientists say.

This study of statistical relationships is the first to establish a link between this class of drugs and cataracts in humans. Prior studies in animal models had demonstrated that SSRIs could increase the likelihood of developing the condition.

"When you look at the trade-offs of these drugs, the benefits of treating depression - which can be life-threatening - still outweigh the risk of.

developing cataracts, which are treatable and relatively benign," says Dr. Mahyar Etminan, main author of the article, a scientist and clinical pharmacist at the Centre for Clinical Epidemiology at Vancouver Coastal Health Research Institute and an assistant professor in the Dept. of Medicine at UBC.

Scientists found patients taking SSRIs were overall 15 per cent more likely to be diagnosed with cataracts or to have cataract surgery.

The degree of risk among specific and different types of SSRIs varied considerably. Taking fluvoxamine (Luvox) led to a 51 per cent higher chance of having cataract surgery, and venlafaxine (Effexor) carried a 34 per cent higher risk. No connection could be made between fluoxetine (Prozac), citalopram (Celexa), and sertraline (Zoloft) and having cataract surgery.

Co-author Dr. Frederick S. Mikelberg, professor and head of the Dept. of Ophthalmology and Visual Sciences at UBC and head of the Dept. of Ophthalmology at Vancouver General Hospital, notes that the average time to develop cataracts while taking SSRIs was almost two years.

"While these results are surprising, and might inform the choices of psychiatry experts when prescribing SSRIs for their patients, they should not be cause for alarm among people taking these medications," Mikelberg says.

SSRIs, the third most prescribed class of drugs in the world, block the uptake of the neurotransmitter serotonin by neurons in the brain, thereby stimulating more impulses between neurons. Cataracts, a clouding of the eye's lens that commonly occurs in older people, are routinely treated through surgery. More than 1.5 million people undergo surgery for the condition every year in North America, as per the Canadian Ophthalmological Society.


Posted by: Mike    Source




Did you know?
Some anti-depressant drugs are linked to an increased chance of developing cataracts, as per a new statistical study by scientists at the University of British Columbia, Vancouver Coastal Health Research Institute and McGill University. The study, based on a database of more than 200,000 Quebec residents aged 65 and older, showed statistical relationships between a diagnosis of cataracts or cataract surgery and the class of drugs called selective serotonin reuptake inhibitors (SSRIs), as well as between cataracts and specific drugs within that class.

Medicineworld.org: Anti-depressants and cataracts

Cancer terms| History of cancer| Imaging techniques| Cancer Main| Bladder cancer news| Cervix cancer news| Colon cancer news| Esophageal cancer news| Gastric cancer news| Health news| Lung cancer news| Breast cancer news| Ovarian cancer news| Cancer news| Pancreatic cancer news| Prostate cancer news| Endometrial cancer news| General info| What is cancer?| Cancer causes| Is cancer hereditary?| Types of cancer| Cancer statistics| Breast cancer main| Breast cancer symptoms| Colon cancer main| Anal cancer| Bladder cancer main| Lung cancer general| Lung cancer main| Non small cell| Small cell| Ovarian cancer main| Treatment of ovarian cancer| Prostate cancer main| Updates in oncology| Acute myeloid leukemia|

Copyright statement
The contents of this web page are protected. Legal action may follow for reproduction of materials without permission.