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From Medicineworld.org: Mesothelioma News Blog

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June 15, 2008, 1:19 PM CT

Carbon Nanotubes Could Have Asbestos-Like Health Complications

Carbon Nanotubes Could Have Asbestos-Like Health Complications

A recent laboratory study has shed new light on the possibility of a nexus between carbon nanotube exposure and the asbestos-like health effects.

Carbon nanotubes are molecular-level structures that are now being used in thousands of products from tennis rackets and hair dryers to computer chips and electronics. They are renowned for their unparalleled strength and remarkably low mass, and were seen by a number of as the next frontier of product durability.

The study, which involved laboratory mice, indicated that upon introduction into the lower abdomen, nanotubes had virtually identical effects as asbestos fibers. When inhaled or ingested, asbestos fibers will become lodged in the pleural lining of the body's internal organs.

Over time, these fibers cause a sustained inflammation of the internal tissue. This inflammation is usually linked to the beginning stages of asbestosis and mesothelioma, a rare form of cancer now only attributed to asbestos exposure.

Like asbestos fibers, nanotubes are extremely durable and cannot be broken down or expelled by natural body function.

While there is no immediate reason for concern, (most nanotubes are securely adhered within structural compounds) there is certainly justification for further research. Those who may potentially be endangered are those who work in the manufacture of these products as well as those who encounter damaged products.........

Posted by: Scott      Read more


June 13, 2007, 12:26 AM CT

Links Between Taconite And Mesothelioma

Links Between Taconite And Mesothelioma
A 240 ton truck carries taconite rock to the crusher building at Hibbing Taconite. (MPR Photo/Bob Kelleher)
The Minnesota Department of Health is launching two major studies to answer long-simmering questions about taconite and human health.

The agency says men in northeastern Minnesota have twice the expected rate of a rare form of cancer called mesothelioma.

It's caused by asbestos, but the Health Department wants to find out whether it can also be caused by fibers in the taconite on the Iron Range.

Duluth, Minn. - Mining, and processing taconite, are dirty, dusty jobs. It's hard to avoid breathing the dust from the taconite, which is crushed to the consistency of talcum powder. And asbestos is still used in some older furnaces and other equipment.

Jim Kelly retired three years ago from the Northshore mine at Silver Bay. He has a spot on one lung that's probably a precursor to asbestosis. It's a disease that causes shortness of breath and chronic coughing, and indicates an increased risk of lung cancer.

But he's not about to blame taconite for that. He worked in other industries, and was exposed to asbestos on several jobs. He's heard claims about the dangers of taconite for 30 years, and he doesn't think they're based on much.

"It appears to me that the scientific community and the medical community cannot come to agreement on what is the specific hazard here," he says. "At least I have to date never heard anything specific."........

Posted by: Scott      Read more         Source


June 13, 2007, 12:16 AM CT

Looking Forward To Asbestos Ban

Looking Forward To Asbestos Ban
A deal is near on legislation banning the use of asbestos, a fibrous mineral often used in brake linings, gaskets, cement products and even yarns and threads imported into the country despite its deadly health risks.

Sen. Patty Murray, D-Wash., a leading advocate of the ban, and Sen. Johnny Isakson, R-Ga., said Tuesday that they are within a week or two of wrapping up a compromise that also would authorize $50 million in research to combat the health effects that have killed as a number of as 231,000 people since 1980 and could claim at least that a number of more by 2040.

The measure has a long road ahead: It must be approved by the Senate Environment and Public Works Committee, then be approved by the full Senate. Then the House of Representatives would have to take up the issue.

But for Murray, Tuesday's committee hearing where the deal was announced was a milestone. It was the first time in the six years she has been pressing for the ban that it had reached the full committee, and the first time passage seems within reach.

"It's shocking to me that it has taken six years, and the deaths of several close friends," Murray said afterward.

The panel's chairwoman, Sen. Barbara Boxer, D-Calif., joined Murray in introducing the ban bill earlier this year.........

Posted by: Scott      Read more         Source


December 23, 2006, 7:31 AM CT

Incredible Story Of Paul Kraus

Incredible Story Of Paul Kraus
What would be more inspiring for mesothelioma patients than listening to the longest mesothelioma survivor in the world? Do you know Paul Kraus? He is the inspiration behind a number of patients with the diagnosis of one of the deadliest forms of cancer called mesothelioma. I have been personally moved by his story.

It was in one those days in June 1997, Paul Kraus was diagnosed with mesothelioma. That has changed his world forever. The cancer was so widespread that he was told there was little hope and that he should go home and get his affairs in order. Fearful and depressed, but not ready to give up, he researched various therapy options. Unlike a number of Paul was not willing to give an unconditional surrender to the one of the most devastating forms of cancer. With the help of his doctors and family, Paul Kraus created his own remarkable path to healing. Today, over nine years later, he continues to enjoy a good quality of life.

"Dr. Andrew Weil wrote that any illness can be conquered through radical lifestyle change because our bodies are made with powerful self-healing capacities. It was hard to make such radical changes, but I was determined to see them through," Paul Kraus said.

During this teleconference, mesothelioma patients and their loved ones can listen to Mr. Kraus summarize his knowledge and insight into this disease. He will discuss how he handled his diagnosis, what he learned about the cancer, and the steps he took to heal his mesothelioma. Subjects include: chemotherapy, surgery, holistic approaches, integrative therapies, vitamins and other supplements, traditional Chinese medicine, mind-body medicine, doctor-patient relationships, and more. Participants can also ask questions of Mr. Kraus and share information and knowledge with each other.........

Posted by: Scott      Permalink         Source


July 12, 2006, 9:18 PM CT

Targeting Mesothelioma

Targeting Mesothelioma
There is exciting news for patients with in the making. Two pharmaceutical companies have started a clinical phase II clinical trial to test the efficacy and activity of a new drug in mesothelioma. This new drug is named as PXD101. This is a small molecule histone deacetylase inhibitor.

National Cancer Institute is sponsoring the current clinical trial with CuraGen. Those who are having a diagnosis of mesothelioma, which is not removable by surgery and who have failed at least one line of chemotherapy are eligible for the clinical trial. The drug PXD101 is given by intravenous infusion once every three weeks.

The researchers are trying to determine if the drug PXD101 has any significant activity on mesothelioma in terms of clinical response. The study is also aimed at determining the safety of the drug and time to treatment failure. The study would also look for any survival advantage resulting from the use of the drug.

Researchers are planning to enroll a total of 37 patients at different sites across the United States.

Histone deacetylase inhibitors have the ability to down-regulate genes such as BCL-XL and VEGF and up-regulate cell-cycle regulating genes, including p21. Researchers say that they are excited to begin the trial and would evaluate PXD101 as a potential treatment for mesothelioma.........

Posted by: Scott      Permalink


June 19, 2006, 9:24 PM CT

Suggest your News Item To Medicineworld

Suggest your News Item To Medicineworld
As you are aware we are the leading publishers of health news on the web. We publish news items in various forms including numerous blogs and news items. We invite you to participate in our new collection.

We are looking for quality news items that would be interesting to our readers. Now you may suggest the news item from your site to be included at Medicineworld.org. Inclusion of news item at our site get instantaneous attention since the item is illustrated from various blog posts. Addition of pictures to the item adds additional attraction to your news item. Inclusion in the Medicineworld.org site brings quality links and visitors to your site.

If you have an interesting news item related to health, share it with Medicineworld.org and we share it with the world.

Suggest your News Item To Medicineworld........

Posted by: Janet      Permalink


May 14, 2006, 1:04 PM CT

What are the risk factors for mesothelioma?

What are the risk factors for mesothelioma?
Working with asbestos is the major risk factor for mesothelioma. A history of asbestos exposure at work is reported in about 70 percent to 80 percent of all cases. However, mesothelioma has been reported in some individuals without any known exposure to asbestos. History of exposure to various other chemicals have been found in some of these patients, but majority of these patients have no understandable risk factors for mesothelioma.

Asbestos is the name of a group of minerals that occur naturally as masses of strong, flexible fibers that can be separated into thin threads and woven. Asbestos has been widely used in many industrial products, including cement, brake linings, roof shingles, flooring products, textiles, and insulation. If tiny asbestos particles float in the air, especially during the manufacturing process, they may be inhaled or swallowed, and can cause serious health problems. In addition to mesothelioma, exposure to asbestos increases the risk of lung cancer, asbestosis (a non-cancerous, chronic lung ailment), and other cancers, such as those of the larynx and kidney.........

Posted by: Scott      Permalink


May 14, 2006, 12:52 AM CT

School Shut Amid Fears Of Asbestos

School Shut Amid Fears Of Asbestos
Officials conducted air-quality tests at a borough elementary school Friday evening, hours after smoke in its basement forced an evacuation and prompted an asbestos scare.

Results of the tests at Merritt Memorial School were not available Friday night, but borough officials said the tests were merely precautionary. The officials said they expected classes to resume on Monday.

"Right now, we plan on having everyone at Merritt Monday, but I will know better once I get the test results," Superintendent Charles Khoury said.

There were conflicting reports throughout the day Friday as to what transpired in a small area under the school gymnasium where contractors were conducting demolition work as part of a renovation project. County officials at first said no asbestos had been disturbed, but borough police said there had indeed been a "fibrous release" of the carcinogenic substance, which was once used in insulation and fireproofing.........

Posted by: Scott      Permalink         Source


January 1, 2006

French Court Allows Asbestos Warship Transfer

French Court Allows Asbestos Warship Transfer Asbestos was commonly used in ship building
The asbestos warship will soon start to its destination in India. A judge at the Paris administrative court ruled that the four groups had raised "no serious doubts" about the legality of the aircraft-carrier Clemenceau's transfer for decontamination in a shipyard in India.

A French court paved the way for a decommissioned warship insulated with asbestos to be sent for scrapping in India, after rejecting petitions by campaigners trying to block its transfer.

French authorities were waiting for the legal green light to tow the ship, currently docked at the French naval base of Toulon, to Alang in northwestern India, home to the world's biggest ship-breaking yard.

"In theory, the Clemenceau can leave," said Joel Alquezar, who represented the French state in court.

Environmentalist group Greenpeace and three anti-asbestos groups have tried for months to block the operation, on the grounds that Indian shipyard workers are not properly protected from the hazards of working with asbestos, which can cause a form of lung cancer.

The groups reject the state's assessment of the amount of asbestos still left inside the Clemenceau, which they estimate at around 100 tonnes.

Lawyers for the campaigners insisted the fight was not over, and said they were considering an appeal to the State Council, France's highest court -- eventhough such an appeal would not prevent the ship's departure.

Marine authorities in Toulon said on Thursday the Clemenceau was ready to leave as soon as it was authorised to do so.
........

Scott      Permalink


December 28, 2005

Car Parts Still Use Asbestos

Car Parts Still Use Asbestos
All major Japanese automakers except Honda Motor Co. used components containing asbestos to build 1.64 million cars, trucks, motorcycles and other vehicles between 1996 and last month, the Japan Automobile Manufacturers Association said Tuesday.

But there is no risk of the carcinogenic material entering the air and harming humans, because the asbestos was kneaded into resin or sealed for use in gaskets, packing and resin materials in the motor vehicles, which also included buses, fire engines and tractors, it said.

The companies are Toyota Motor Corp., Suzuki Motor Corp., Isuzu Motors Ltd., Nissan Motor Co., Nissan Diesel Motor Ltd., Hino Motors Ltd., Mitsubishi Motors Corp., Mitsubishi Fuso Truck & Bus Corp. and Yamaha Motor Co.

Suzuki Motor made 1.01 million vehicles with parts containing asbestos, the largest among the nine, while Toyota had 27,000 vehicles.

None of the nine companies plans to recall the parts, the association said.

Support package nod

The government endorsed a financial support package Tuesday for people made ill by asbestos and family members of people who have died from such diseases.

Under the terms of the package, 3 million yen would be paid as condolence money and funeral fees to those who have lost relatives to asbestos-linked diseases who were not covered by existing industrial accident insurance schemes.

Patients would receive medical expenses as well as 100,000 yen in monthly recuperation money, government officials said.........

Scott      Permalink


December 27, 2005

Phase III Clinical Trial on Pleural Mesothelioma

Phase III Clinical Trial on Pleural Mesothelioma
Emory Winship Cancer Institute will be one of two facilities in Georgia to conduct a phase III clinical trial of Vorinostat (oral suberoylanilide hydromaxic acid) in patients with advanced cancerous pleural mesothelioma. The purpose of the study is to test the safety and efficacy of Vorinostat as well as to compare the overall survival associated with therapy of the drug.

A rare but devastating disease, it is estimated that 2,000 to 3,000 new mesothelioma cases will be diagnosed each year in the United States. Mesothelioma is cancer of the cells found in the mesothelium, which is the protective lining covering most of the internal organs of the body. Pleural mesothelioma is the most common type of mesothelioma, and it is identified by the presence of malignant cells located in the tissue outside of the lungs and inside of the ribs.

Vorinostat is an experimental drug that is believed to work against cancer cells. When cells become malignant, chemical reactions inside the cancer cell allow those cells to multiply out of control. Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

The principal investigator on the Vorinostat clinical trial at Winship is Dong M. Shin, MD, Professor of Hematology/Oncology and Otolaryngology; Director of Clinical and Translational Cancer Prevention Programs; and Co-Director of the Lung and Aerodigestive Tract Malignancies Program at Emory Winship Cancer Institute. Dr. Shin joined Winship in 2003 after more than 15 years as a faculty member at M.D. Anderson Cancer Center in Houston and the University of Pittsburgh Cancer Institute.

"This is a very important study for this terrible disease," said Dr. Shin. "As a second line treatment, there are currently no options other than this clinical trial."........

Scott      Permalink


December 25, 2005, 10:32 AM CT

Merry Christmas To All Our Readers

Merry Christmas To All Our Readers
Medicineworld wishes all our readers merry Christmas.

Oh, jingle bells, jingle bells

Jingle all the way

Oh, what fun it is to ride

In a one horse open sleigh

Jingle bells, jingle bells

Jingle all the way

Oh, what fun it is to ride

In a one horse open sleigh........

Daniel      Permalink

  • Jury Finds Chrysotile Asbestos Causes Rare Peritoneal Mesothelioma (November 23, 2005)
  • Strong Against Proposed Asbestos Mesothelioma Legislation (November 23, 2005)
  • Second International Mesothelioma Symposium (November 16, 2005)
  • Exposure to Some Rock Powder Can Cause Malignant Mesothelioma (October 17, 2005)
  • Elevated Protein Levels Linked to Mesothelioma (October 17, 2005)



  • Did you know?
    Mesothelioma is a rare type of cancer that arises from the lining that covers the lung called mesothelium. Mesothelioma is usually diagnosed by doing a biopsy of the pleural lining of the chest wall and the mesothelioma diagnosis is established by examining the biopsy tissue under the microscope.

    Medicineworld.org: Mesothelioma News Blog



    Chemotherapy of malignant mesothelioma| Clinical features of mesothelioma| Determination of stage in malignant mesothelioma| Diagnosis of mesothelioma| Do family members of asbestos workers have a higher risk of mesothelioma| Epidemiology of mesothelioma| Frequently asked questions faq in mesothelioma| Gene therapy of mesothelioma| History of asbestos and mesothelioma| History of asbestos associated mesothelioma| How does asbestos cause mesothelioma| Mesothelioma| Mechanism of asbestos cancer induction| Mesothelioma with no history of asbestos exposure| Molecular basis of mesothelioma| Multimodality treatment of malignant mesothelioma| Natural history of malignant mesothelioma| Radiation therapy for malignant mesothelioma| Staging of pleural mesothelioma| Surgical control of pleural effusion| Surgical treatment of malignant mesothelioma| Who are at high risk for development of mesothelioma|

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