From Medicineworld.org: Myasthenia gravis
I. Ocular myasthenia (15-20%)
II. A. Mild generalized myasthenia with slow progression; drug responsive (30%). B. Moderately severe generalized myasthenia; severe skeletal and bulbar involvement but no crises; drug response less than satisfactory (25%)
III. Acute fulminating myasthenia; rapid progression of severe symptoms with respiratory crises and poor drug response; high mortality (15%)
IV. Late severe myasthenia; symptoms as above, but resulting from steady progression over 2 years from class I to class II
What are the symptoms of Myasthenia gravis?
complain of inability to fix their hair because of the fatigue of their shoulders. There is more weakness towards the end of the day.
Fluctuating weakness is present. The weakness may vary over minutes or days. Prolonged changes are called remissions and exacerbations. Involvement of the respiratory muscles produces difficulty in breathing. It occurs in 10% of the myasthenia patients. There is increasing weakness during menstruation, exposure to very hot and cold climates and after vaccination.
Sometimes tingling and numbness of the face, hand and thighs occur, but it's very mild.
As the name implies, Myasthenia gravis is a muscular weakness with bad prognosis. Repeated or persistent activity of muscle group exhausts its contractile power, leading to weakness of the muscle. Rest restores the strength of the muscle to some extent. The onset of weakness is insidious, but in some patients it is fairly rapid. Some cases are initiated by emotional upset or respiratory tract infection. Once the disease begins, slow progression follows.
Usually muscles of the eyes are affected initially. It produces drooping of the eyelid (ptosis) and patient complaints of double vision (diplopia).Eye muscles are involved in more than 90% of the cases of myasthenia gravis. When the patient looks upwards for a prolonged period of time, the ptosis is exaggerated.
Muscles of mastication (chewing), facial expression (laughing, crying, blowing etc.,) and swallowing and speech are affected. Brain stem involvement produces difficulty in speaking and swallowing. The natural smile may become transformed into a snarl. Chewing food will be difficult and the patient may have to terminate a meal. Women may
What are the tests to find out myasthenia gravis?
Treatment of myasthenia gravis
Did you know?
Myasthenia gravis can occur at any age. Females are more commonly affected and at an earlier age. Females are affected at the age of 10-40 years and males from 50-70 years. Prevalence is 3 cases per100, 000 in the U.S. Familial cases are few.
Medicineworld.org: Myasthenia gravis
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