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Do You Read All Of Our Cancer Blogs?

Do You Read All Of Blogs?
This page you have reached is an archive page of cancer blog. If you wish to read current posting of this blog, please go to cancer blog main page. If you wish to read the archived blog postings, simply scroll down to the lower part of the page.

Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Janet      

Dec 28, 2005

New Indication For Femara

New Indication For Femara
Until now FDA has approved Femara for use in women with metastatic disease and women with early stage breast cancer switching from tamoxifen. FDA has now extended the indication for treatment with Femara to the first treatment of women with early stage breast cancer who are hormone receptor positive.

Femara belongs to the group of aromatase inhibitors with other drugs like arimidex and aromasin. Recent clinical trials have shown that aromatase inhibitors are superior to tamoxifen in both adjuvant therapy and treatment of advanced breast cancer.

"Right now we're only getting about 7 percent of the early adjuvant market, so there's a lot of room for growth," said David Epstein, chief executive officer of Novartis Oncology

The most prescribed product for this market is Arimidex, which has a market share of roughly 50 percent, Epstein said. Tamoxifen has about 40 percent of the market, and other drugs, including Aromasin and Femara have the rest.

Sherin      Permalink


Dec 27, 2005

Prostate Cancer Treatment And Bone Loss

Prostate Cancer Treatment And Bone Loss
Hormonal therapy is the main form of treatment for prostate cancer. This hormonal therapy may come at a cost as per a new study, which suggest that prolonged hormonal therapy may be associated with bone loss.

Researchers at the University of Pittsburgh compared the bone health of 152 men with prostate cancer to that of healthy men, for one year. About half the cancer patients had not received hormonal therapy, 30 had received it for less than six months, while 50 had received it for six months or more.

Healthy men and cancer patients who had not undergone hormonal treatment showed no bone loss, the researchers report in the December issue of the Journal of Clinical Endocrinology and Metabolism.

But those who had recently started hormonal therapy showed a loss of bone mineral density ranging from 1 percent to 4 percent.

"Men with prostate cancer who are initiating androgen deprivation therapy have a 5- to 10-fold increased loss of bone density at multiple skeletal sites," compared to men not on this therapy, the researchers concluded.

Based on the findings, they suggested that patients receiving this type of hormonal therapy also receive concurrent treatment aimed at slowing or stopping bone loss, especially in the first year after such therapy begins.

Mark      Permalink


Dec 27, 2005

Biggest Cancer News Of 2005

Biggest Cancer News Of 2005
What's the single most important cancer news in the year 2005? Experts say that discovery of effectiveness of Herceptin (trastuzumab) in the early stage of breast cancer is the single and most important cancer news of the year 2005. These researchers point out that the effect of Herceptin was dramatic in these patients and cut down the risk of recurrence of breast cancer in half.

In the opinion of Linda Vahdat, who is the head of the breast cancer program at Weill Medical College of Cornell University this is the biggest news of the year.

Herceptin is effective in breast cancer that over-expresses Her2 gene. About 20 to 30 percent of all women who are diagnosed with breast cancer may have over expression of this gene and hence may be candidates for treatment with Herceptin. In these patients Herceptin is used in combination with chemotherapy.

Clinical trial results presented at the American Society of Clinical Oncology meeting in May 2005, use Herceptin and chemotherapy reduce the risk of recurrence of breast cancer in patients who over-expresses Her-2 gene by 52 percent. The risk of dying from breast cancer was reduced by about one third.

However Herceptin is not for every woman with Her2-gene amplification. Herceptin has a significant side effect of causing damage to the heart muscle. So caution should be exerted in using this drug in women who has only very low risk of breast cancer recurrence, since the risk of taking Herceptin may be more than the benefit in these women. Recently Genentec the makers of the drug and FDA have issued a warning stating that combined use of Herceptin (trastuzumab) and chemotherapy may significantly increase the risk of toxicity for the heart and should be used with caution.

Sherin      Permalink


Dec 26, 2005

New Colon Cancer Guidelines From NCCN

New Colon Cancer Guidelines From NCCN
The National Comprehensive Cancer Network (NCCN) is proud to announce several new updates to the NCCN Colon Cancer Guidelines. The changes highlight cutting-edge developments in the treatment of colon cancer and represent the recognized standard for clinical policy in oncology in both the community and the academic practice settings.

The latest version of the NCCN Colon Cancer Guidelines include several major changes to recommended courses of treatment based on recent relevant clinical studies and changing practice patterns. One significant change is the recommendation that all first-line therapy for advanced or metastatic disease should include bevacizumab (Avastin) in the treatment regimen. The panel also added a new regimen, capecitabine (Xeloda) and oxaliplatin (Eloxatin) also known as CAPOX as a treatment option in first-line therapy.

In addition to changing treatment recommendations in advanced or metastatic disease, there are also new options in the adjuvant setting. The panel added new treatment regimens for Stage IIA patients, including capecitabine, 5-FU/leucovorin or 5-FU/leucovorin/oxaliplatin.

Also, a new section entitled "Principles of Pathologic Review" has been added to the NCCN Colon Cancer Guidelines to provide detailed information regarding issues such as adequate lymph node evaluation required for accurate staging and the sentinel lymph node and detection of micrometastasis by immunohistochemistry.

NCCN Clinical Practice Guidelines in Oncology(TM) are developed and updated through a consensus-driven process with explicit review of the scientific evidence by multidisciplinary panels of expert physicians from NCCN member institutions. The most recent version of this and all the guidelines are available for free at www.nccn.org.

Sue      Permalink


Dec 26, 2005

Black Smokers More Susceptible to Lung Cancer

Black Smokers More Susceptible to Lung Cancer
There are inherent difference between African Americans and Caucasians when it comes to risk factors for lung cancer. A positive family history of lung cancer may be more significant for African Americans than Caucasians.

This is based on a recently published research data from Wayne State University. Detroit researchers found that having a parent, grandparent or sibling with lung cancer before the age of 50 poses a higher risk for African Americans than Caucasians.

Researchers evaluated more than 7,500 first-degree relatives of 700 people who developed lung cancer at an early age. They compared them with a cancer-free control group.

By age 70, 25 percent of African Americans who were smokers and had a close relative with lung cancer developed cancer versus only 17 percent of white.

African Americans with a family history of lung cancer were twice as likely to develop lung cancer as Caucasians, after factoring in other risk factors.

Scott      Permalink


Dec 26, 2005

Axillary Lymph Node Surgery Not Required In Some Older Patients

Axillary Lymph Node Surgery Not Required In Some Older Patients
Aim of breast cancer surgery is to remove the breast tumor and remove any possible involvement of lymph nodes. Since lymph nodes in the axilla (arm -pit) is a very common site for cancer spread, breast cancer surgery often involves removal of axiallary lymph nodes as well.

There are two common methods for removal of axillary lymph nodes. A surgeon may initially do a sentinel lymph node biopsy and may proceed to clearing of the lymph nodes in the axilla only if the sentinel lymph node is positive. On the other hand your surgeon may proceed straight to axillary lymph node dissection without first doing a sentinel lymph node biopsy. In any case axillary clearance of lymph nodes is very important in patients suspected of axillary lymph node involvement.

While this is very important in younger women, the question is should we go for a complete axillary clearance for older patients. A recent study published in the Journal Of Clinical Oncology suggests this is un-necessary.

In this study of 473 patients who were aged more than 60 years, clinically node negative and received hormonal therapy for hormone positive tumor the investigators noted no difference between the groups who had axillary clearance and those who had extensive surgery.

Bottom line: If you are sixty years or older, and have no lymph nodes felt by physical examination, the tumor is hormone receptor positive and willing to take hormonal therapy then there is no need for that disfiguring surgery. No need for cherry picking of lymph nodes.

Sherin      Permalink


Dec 25, 2005

Merry Christmas From Medicineworld.org

Merry Christmas From Medicineworld.org
Medicineworld wishes all our readers merry Christmas.

Oh, jingle bells, jingle bells
Jingle all the way
Oh, what fun it is to ride
In a one horse open sleigh
Jingle bells, jingle bells
Jingle all the way
Oh, what fun it is to ride
In a one horse open sleigh

A day or two ago
I thought I'd take a ride
And soon Miss Fanny Bright
Was seated by my side
The horse was lean and lank
Misfortune seemed his lot
We got into a drifted bank
And then we got upsot

Oh, jingle bells, jingle bells
Jingle all the way
Oh, what fun it is to ride
In a one horse open sleigh
Jingle bells, jingle bells
Jingle all the way
Oh, what fun it is to ride
In a one horse open sleigh yeah

Janet      Permalink


Dec 25, 2005

Do You Read All Of Our Medical Blogs?

Do You Read All Of Our Medical Blogs?
Do you read all of the medical blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on various medical topics. Medicieworld.org is publishing a wide variety of blogs on different topics.

Breast cancer blog: Breast cancer blog is run by Janet and colleagues. Latest post from this breast cancer blog reads as follows: Location of Breast Cancer Does Matter - Does it really matter which part of the breast you develop cancer? Researchers say yes.
Researchers from Switzerland recently reported that women with early breast cancer in the lower inner quadrant (the lower part of the breast, closer to the center of the body) are twice as likely to die of their cancer as women with cancer diagnosed in other parts of the breast. Researchers speculate this could be due to undetected spread of the cancer to the lymph nodes of the internal mammary chain (lymph nodes near the center of the chest). These lymph nodes are difficult to be evaluated for the presence of cancer.......

Lung cancer blog: Lung cancer blog is run by Scott and colleagues. Latest post from this lung cancer blog reads as follows: Cancer Death Rate Continues to Drop in U.S. - It is comforting to know that the cancer death rates continue to drop and cancer diagnosis rate continue to be stable in the United States. This is true for most of the common types of cancer including breast cancer, lung cancer, colorectal cancer and the prostate cancer. This information is released by the National Cancer Institute.......

Colon cancer blog: Colon cancer blog is run by Sue and colleagues. Latest post from this cancer blog post reads as follows: Cancer Death Rate Continues to Drop in U.S. - It is comforting to know that the cancer death rates continue to drop and cancer diagnosis rate continue to be stable in the United States. This is true for most of the common types of cancer including breast cancer, lung cancer, colorectal cancer and the prostate cancer. This information is released by the National Cancer Institute...............

Prostate cancer blog: Prostate cancer blog is run by Mark and colleagues. Latest post from this prostate cancer blog reads as follows: Cancer Death Rate Continues to Drop in U.S. - It is comforting to know that the cancer death rates continue to drop and cancer diagnosis rate continue to be stable in the United States. This is true for most of the common types of cancer including breast cancer, lung cancer, colorectal cancer and the prostate cancer. This information is released by the National Cancer Institute...............

We have a diabetes watch blog as well and this is run by JoAnn and colleagues. The latest post from this diabetes watch blog reads as follows: Health Canada Issues Warning For Avandia and Avandamet - Health Canada is issuing warnings for two commonly used drugs to treat Type-2 diabetes. The warning states that use of these drugs may lead to new cases or worsening of a vision problem called macular edema.......

Heart watch blog: Heart watch blog is run by Daniel and colleagues. The latest post from this heart watch blog reads as follows: Fish Oil Combats Heart Problem Related To Pollution - You probably can't do much to improve the air pollution around you, but now you can protect yourself from some of the harmful effects of air pollution on the heart. A new research finding suggests that daily supplementation with omega-3 fatty acid (fish oil) prevents a potentially-deadly decline in heart rate variability (HRV) associated with exposure to indoor air pollution, researchers from the US and Canada report......

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. The latest post from this cancer blog reads as follows: Pancreatic Cancer: Looking Forward To Skin Rash! - Probably you all know that a new drug combination Tarceva and Gemzar has been FDA approved recently for the treatment of pancreatic cancer. Did you know that, if you are developing a bad skin rash while on this treatment it is a good sign! I am not kidding, the study that led to the approval of this combination was presented in the American Society of Clinical Oncology meeting in 2005. This study has shown that the combination of Tarceva and Gemzar works best in patients who had a bad skin rash!......

Scott      Permalink


Dec 24, 2005

Pancreatic Cancer: Looking Forward To Skin Rash!

Pancreatic Cancer: Looking Forward To Skin Rash!
Probably you all know that a new drug combination Tarceva and Gemzar has been FDA approved recently for the treatment of pancreatic cancer. Did you know that, if you are developing a bad skin rash while on this treatment it is a good sign! I am not kidding, the study that led to the approval of this combination was presented in the American Society of Clinical Oncology meeting in 2005. This study has shown that the combination of Tarceva and Gemzar works best in patients who had a bad skin rash!

Skin rash is a very common side effect of Tarceva. Past studies have shown a co-relational between skin rash and the activity of the drug. In this Tarceva Gemzar study patients were divided into three groups based on the severity of skin rash. The first group comprised of patients who had no skin rash and the second group comprised of patients who had mild skin rash and the third group comprised of patients who had significant or severe skin rash.

When the investigators analyzed the data, they found that patients who developed significant or severe skin rash performed much better compared to the other two groups. The median survival in patients who had no skin rash or mild skin rash was 5 months while those who developed significant or sever skin rash lived a median period of more than 10 month. Only 16 percent of patients who had no skin rash and 11 percent of patients who had only mild skin rash were alive at one year after starting treatment. Compared to this poor performance, 43 percent of patients who had significant or severe skin rash were alive at one year after starting treatment

So if you are on Tarceva and Gemazar for the treatment of pancreatic cancer, look forward to your bad skin rash. That may be your lifeline.

Janet      Permalink


Dec 23, 2005

Cancer Death Rate Continues to Drop in U.S.

Cancer Death Rate Continues to Drop in U.S.
It is comforting to know that the cancer death rates continue to drop and cancer diagnosis rate continue to be stable in the United States. This is true for most of the common types of cancer including breast cancer, lung cancer, colorectal cancer and the prostate cancer. This information is released by the National Cancer Institute.

The stabilization of the cancer diagnosis rate shows that Americans are taking some steps to help prevent cancer, the agency said, and the use of some screening tests is at high rates in an effort to detect cancers early.

"The overall message of the report remains positive," NCI Director Andrew C. von Eschenbach said in releasing the report. "The evidence that I have seen convinces me that we are poised to make dramatic gains against cancer in the near future."

The rate of new cases of cancer was 488.6 per 100,000 Americans in 2002, close to the rate of 488.1 a year earlier.

At the same time, the death rate for all cancers was 193.6 per 100,000, down from 195.7 a year earlier and continuing a steady downward trend. Death rates for prostate cancer showed, 28.0 per 100,000, down from 28.9, breast cancer death rates were down to 25.4, from 26.0, colorectal cancers were down to, 19.6, from 20.1 and lung death rates were down to 54.8 from 55.2.

Smoking by youths, which had been growing in the 1990s, has been declining since 1997, the report said. Youths are starting to smoke later, with average age for first use of cigarettes at 15.4 in 2003, up from 14.9 a decade earlier. And the percentage of high schoolers who smoked cigarettes fell from 30.5 percent to 21.9 percent in the same period.

Janet      Permalink




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Cancer
Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable.

Cancer Blog: From Medicineworld.org

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