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Do You Read All Of Our Blogs?

Do You Read All Of Blogs?
This page you have reached is an archive of old blog posting. Just follow the links below to go to the main blog pages to read the latest blog posting.

Do you read all of the blogs published by medicineworld.org? Many of our bloggers are busy keeping you updated on the various health related topics. We publish the following blogs at this time.

Cancer blog: I manage the cancer blog with lots of help and support form other bloggers. Through this cancer blog my friends and I try to bring stories of hope for patients with cancer. The cancer blog often republishes important blog posts from other cancer related blogs at Medicineworld.org. If you are searching for a blog that covers wide variety of cancer topics, this may be the one for you.

Breast cancer blog: Breast cancer blog is run by Emily and other bloggers and they bring you the latest stories, news and events that are related to breast cancer. Increasing awareness about breast cancer among women and in the general population is the main goal of this breast cancer blog.

Lung cancer blog: Lung cancer blog is managed by Scott with the help of other bloggers. Through this blog Scott and his friends constantly remind the readers about the dangers of smoking. It's a never-ending struggle against this miserable disease with which a social stigma of smoking is associated.

Colon cancer blog: Colon cancer blog is run by Sue and other bloggers. Sue brings a personal touch to the colon cancer blog since her mother died of colon cancer few years ago. She writes about stories, research news and advances in treatment related to colon cancer.

Prostate cancer blog: Prostate cancer is the most common cancer among American men. American Cancer Society estimates that over 230,000 new cases of prostate cancer occur in the United state every year. This important blog about prostate cancer is run by Mark and other bloggers. This blog brings news, stories, and other personal observations related to prostate cancer.

Medicineworld.org publishes a diabetes watch blog and this blog is run by JoAnn other bloggers. This diabetes watch blog brings you the latest in the field of diabetes. This includes personal stories, advances in diagnosis and treatment, and other observations about diabetes. Improving awareness about diabetes is an important mission of this group.

Heart watch blog: About 13 million Americans suffer from coronary artery disease. Coronary artery disease is the leading cause of death in American men and women amounting a staggering 20 percent of all causes of death. The tremendous responsibility of running a heart blog is entrusted to Daniel. He is creating blog posts with the help and support of other bloggers.

Janet      

Oct 19, 2005

New Radiation Technique Could Avoid Loss Of Hair For Brain Cancer Patients

New Radiation Technique Could Avoid Loss Of Hair For Brain Cancer Patients
Patients receiving radiation therapy to the brain may lose their hair due to the effect of radiation to the scalp. In future it may be possible for such patients to avoid hair loss. According to a new study presented at the annual meeting of American Society for Therapeutic Radiology and Oncology, patients whose are receiving radiation therapy to brain can avoid hair loss when treated with newer radiation techniques, thereby improving their quality of life.

Most brain cancer patients whose cancer has spread to the brain receive whole brain radiotherapy, in which two simple radiation beams on each side of the head are used to target the cancer. It also causes patients to lose the hair on their head. Doctors are experimenting with new types of radiation therapy to see if they are as effective in treating the cancer while preventing hair loss.

Doctors were able to improve upon whole brain radiation therapy in the patients under study, by using intensity modulated radiation therapy. Half of the patients in the study reported only slightly noticeable hair loss four weeks after treatment ended, and half had no noticeable hair loss.

"This new study will encourage doctors to consider using this new radiation technique to treat cancer that has spread to the brain," said Todd Scarbrough, M.D., lead author of the study and a radiation oncologist at the MIMA Cancer Center in Melbourne, Florida.

Janet      Permalink

Oct 19, 2005

Marijuana Use Does Not Increast Cancer Risk

Marijuana Use Does Not Increast Cancer Risk
Marijuana and tobacco are chemically similar, but this does not mean that use of marijuana results in equally increased risk of development of cancer. In this review that is to be published in the an upcoming issue of the journal Harm Reduction Dr. Robert Melamede of the University of Colorado, Colorado Springs writes about this topic.

Tobacco and marijuana smoke differ in a number of ways, one notable example is that marijuana smoke contains tetrahydrocannabinol (THC), while tobacco smoke contains nicotine. Nicotine increases the cancer-promoting effects of smoke, while THC reduces cancer promoting effects, Melamede explained.

THC and nicotine act on related cellular pathways, but despite this fact, they bind to different receptors to activate these pathways. Cells in the lungs and respiratory passages are lined with nicotine receptors but these cells don't appear to have THC receptors. This may explain why smoking marijuana has so far not been linked with lung cancer, a major cause of death from cigarette smoking.

Research has also shown that marijuana kills cancer cells and reduces tumor growth. This is, in part, because marijuana reduces the formation of blood vessels that nourish tumors.

This news in no way should be comforting for a marijuana smoker since the effects of marijuana are complex and sometimes contradictory. Many people may use marijuana and tobacco together, and the two drugs could interact in complex ways.

While some governments are reluctant to approve marijuana for medicinal use, the review noted that there's increasing evidence that marijuana can improve the lives of patients with a broad range of health problems, including insomnia, AIDS, multiple sclerosis and Alzheimer's disease.

Janet      Permalink

Oct 18, 2005

Eliminating Lung Cancer Mortality By 2015

Eliminating Lung Cancer Mortality By 2015
National cancer institute (NCI) is initiating an integrated effort to eliminate mortality from lung cancer by the year 2015.

The integrated strategy is to focus on three critical issues related to lung cancer. These critical strategies include more effective tobacco control, improving likelihood of cure for lung cancer by developing methods of earlier detection and improving treatment of pre-malignant lung lesions and lung cancer with development of new targeted therapies.

NCI has the following recommendations to achieve this goal by the year 2015.

More effective tobacco control:
Emphasis will be given to development and testing of promising therapies for nicotine addiction. Research would be targeted to explore the genetics of nicotine addiction focusing on gene-environment interaction.

Early detection:
Focus will be given to develop more effective proteomic and expression technologies on tissues and bio-specimen samples. Effort will be directed at studying markers expressed on malignant tissues.

Improving treatment:
Priorities will be given to development of new drugs and understanding patient's response to therapy. The team has suggested research on the early cancer and pre-cancer microenvironment.

Janet      Permalink

Oct 18, 2005

Is CT colonography Cost Effective?

Is CT colonography Cost Effective?
Image courtesy of
University of Chicago
CT colonography is a relatively new imaging technology that can be used to examine the large bowel and rectum where these cancers occur. It is a noninvasive technique that reveals cancer lesions and polyps with nearly the same sensitivity and specificity as colonoscopy, without the risks of bowel perforation.

A study by Heitman and colleagues from Canada compares the costs and effectiveness of CT colonography to the conventional colonoscopy for screening. They found that screening 100 000 patients with CT colonography would cost $2.3 million more (in Canadian dollars) than with colonoscopy, and would avoid 3.8 fatal perforations, but at the same time, this method would lead to 4.1 cancer-related deaths from polyps not seen with CT, which would later become malignant. (Colonoscopy is slightly more sensitive than CT colonography, and could be expected to detect a certain number of polyps that the CT method would miss.)

New technologies are always attractive. Because CT colonography does not physically invade the body, it has even more appeal, it is easier for patients to accept. Its cost, however, is much higher, and its benefit (in terms of years of living that are gained) is only slightly lower than when colonoscopy is used.

Janet      Permalink

Oct 17, 2005

Does type2 diabetes effect prostate cancer?

Does type2 diabetes effect prostate cancer?
As per the research findings presented by researchers at Fox Chase Cancer Center there no effects of type II diabetes on aggressiveness of prostate cancer but found that long-term survival is worse in patients with type II diabetes and prostate cancer. These findings were presented at the 47th Annual Meeting of the American Society for Therapeutic Radiology and Oncology in Denver.

Khanh H. Nguyen, M.D., lead author of the Fox Chase study and a resident in the radiation oncology department at Fox Chase said that men with type II diabetes didn't have a significantly different initial profile for their prostate cancer than the men without diabetes. The study did not detect significant differences in the initial PSA, Gleason score, or T-stage between the men with and without diabetes. Men with type II diabetes did not have significantly different treatment outcomes, said Nguyen.

Nguyen, now a radiation oncologist at the University of Tennessee Medical Center in Knoxville, Tenn., concluded, "The degree of hyperinsulinemia in type II diabetes can vary considerably and may obscure the true impact of insulin on the natural history of prostate cancer. "However, type II diabetes conferred a significantly higher overall mortality. Aggressive management of diabetes with diet, exercise, and medications may improve the survival of cancer patients."

Janet      Permalink

Oct 17, 2005

Cancer Patients Use of Complementary Medicine Hiding From Doctors

Cancer Patients Use of Complementary Medicine Hiding From Doctors
People with cancer believe that it takes more than modern medicine to help them. Most of them rely on prayer, relaxation techniques, exercise and sometimes herbs or mega-vitamins for improving their health. But fewer than half of them discuss using complementary therapies with their doctors.

According to a recent study presented at the American Society for Therapeutic Radiology and Oncology's 47th Annual Meeting in Denver almost half (48 percent) of cancer patients treated with chemotherapy and radiation are using at least one type of complementary and alternative medical therapy (CAM) treatment, a majority of them (75 percent) don't tell their doctor, even while receiving conventional cancer treatment.

The study shows that CAM use is almost twice as prevalent among patients treated by only chemotherapy (65 percent), compared to those treated by only radiation (35 percent).

"This study shows the significant lack of communication between patients and their doctors about the use of complementary and alternative medicines, like vitamins and herbs," said Neha Vapiwala, M.D., lead author of the study and a radiation oncologist at the University of Pennsylvania in Philadelphia.

"It's important for doctors to know about their patients' CAM use and to understand patients' reasons for using it, so that they can better tailor and optimize treatment regimens and improve patient quality of life during radiation and/or chemotherapy."

Janet      Permalink

Oct 16, 2005

Gene therapy with radiation block prostate cancer in mice

Gene therapy with radiation block prostate cancer in miceResearchers at Montefiore Medical Center have discovered that a combination of anti-gene therapy based on angiogenesis and radiation inhibits the growth of prostate and lung cancer tumors in mice increasing their lifespan. This exciting result was reported at the recent meeting of American Society of Therapeutic Radiation and Oncology (ASTRO in Denver, CO.

The gene therapy involves a new protein, called Tek-Fc, which blocks angiogenesis, or the growth of blood vessels that are crucial for the continued growth of tumors.

"This anti-angiogenic gene therapy could eventually be an effective adjuvant to radiation therapy in the treatment of prostate and lung cancer in humans," said Madhur Garg, MD, lead author of the study and a senior physician scientist in Montefiore's Department of Radiation Oncology, the only institution in the US using this specific gene therapy model.

Dr. Garg and his colleagues at Montefiore and Albert Einstein College of Medicine demonstrated that a combination of Tek-Fc protein therapy and radiation was effective in reducing the size and inhibiting the growth of prostate and lung tumors in mice significantly.

Janet      Permalink

Oct 15, 2005

Pre-operative chemo-radiation Prevents Local Relapse of Rectal Cancer

Pre-operative Chemo-radiation Prevents Local Relapse of Rectal Canceriv chemotherapyPre-operative combination of chemotherapy and radiation may improve outcomes in rectal cancer as per a recent study by German researchers. These researchers working with 26 different hospitals randomly assigned a total of 799 patients with clinical stage II or stage III rectal cancer to receive chemo-radiation either before or after surgery using the drug 5-FU.

Patients in the before-surgery group completed chemoradiation treatment six weeks before surgery. Those in the other group had surgery first, followed by the same chemoradiation regimen, except for a radiation boost delivered to the area where the tumor was removed. Afterwards, patients in both groups received additional treatment with 5-FU.

After a median follow-up period of just under four years, six percent of patients in the before-surgery group had had a local relapse, compared with 13 percent in the after-surgery group. Similar numbers of patients in both groups (36 percent for the before-surgery group; 38 percent for the after-surgery group) had a relapse elsewhere in the body.

Overall survival at five years was 76 percent for the before-surgery group and 74 percent for the after-surgery group. However, this difference was not statistically significant.

Overall, fewer patients in the before-surgery group suffered severe short-term or long-term side effects of treatment, such as diarrhea and the development of narrowings where the bowel was reconnected after removal of the tumor.

Some patients at the start of the trial had tumors that surgeons thought would require the complete removal of the rectum; this, in turn, would require a permanent colostomy (that is, creation of an opening in the wall of the abdomen to allow removal of waste from the body). Among these patients, the before-surgery group was more likely to avoid a colostomy - their rate of bowel reconnection after tumor removal was more than double that of the after-surgery group.

Janet      Permalink

Oct 15, 2005

Phase 3 trial using talabostat in metastatic non-small cell lung cancer

phase 3 trial in non-small cell lung cancerPoint Therapeutics, Inc. has announced that it initiated its Phase 3 program in metastatic non-small cell lung cancer (NSCLC). This news follows a successful End-of-Phase 2 meeting with the Food and Drug Administration.

"We are pleased with our End-of-Phase 2 meeting discussions with the FDA and the fact that there were no major changes to the Phase 3 study protocols. We look forward to continuing to clinically develop talabostat in this advanced lung cancer population," said Dr. Margaret Uprichard, chief development officer and senior vice president of Point Therapeutics.

Point's Phase 3 program will further evaluate the company's lead compound, talabostat, in patients with Stage IIIB and IV NSCLC after failure of a platinum-based chemotherapy. The program will consist of two randomized, double-blind, placebo-controlled trials in up to 800 patients at approximately 100 sites in North America. The first 400-patient trial has opened to enrollment. This trial will evaluate talabostat in combination with docetaxel versus docetaxel with placebo.

The second 400-patient trial will evaluate talabostat in combination with pemetrexed versus pemetrexed with placebo. Docetaxel and pemetrexed are the current standard of care in this advanced patient population. The primary study endpoint is progression-free survival. Secondary endpoints include overall survival, objective response rate, complete response, duration of response and quality of life.

"I am encouraged by the positive results in Point's Phase 2 trial of talabostat and docetaxel. As reported at this year's ASCO meeting" said Dr. Casey Cunningham, an oncologist at Mary Crowley Medical Research Center in Dallas. "Five patients demonstrated at least a 50 percent reduction in tumor size, of which two had a complete response, defined as a complete disappearance of their tumor. To see complete responders in a second or third line setting in advanced non-small cell lung cancer is rare and merits further study.

Talabostat is taken orally and has the potential to be used in both solid and hematologic malignancies and in combination with a range of chemotherapies, monoclonal antibodies and other forms of cancer treatment, according to the company.

Contact information
Tel: 617-933-2130
mail to: inquiries@pther.com

Phase II trial results using talabostat

Janet      Permalink

Oct 15, 2005

Turmeric effective in prevention of breast cancer to lungs in mice

Turmeric effective in prevention of breast cancer to lungs in miceCurcumin, the main ingredient of turmeric and the compound that gives curry its mustard-yellow color, inhibits metastasis to the lungs of mice with breast cancer, report scientists at The University of Texas M. D. Anderson Cancer Center.

Though the study results are early, scientists found that the nontoxic natural substance not only repelled progression of the disease to the lungs, but also appeared to boost the effects of taxol, a usually prescribed chemotherapy for breast cancer.

"We are excited about the results of the study and the possible implications for taking the findings into the clinic in the next several years," says Bharat Aggarwal, Ph.D., professor of cancer medicine in M. D. Anderson's Department of Experimental Therapeutics. "At this time, advanced breast cancer is a difficult foe to fight with few proven treatments available after surgery, chemotherapy and radiation therapy."

Scientists studied 60 mice with breast cancer, which were randomly assigned to one of four groups: control group, Taxol only, curcumin only and the combination of Taxol and curcumin. After the tumors grew to 10 mm (about the size of a pea), they were surgically removed, and the mice were fed a powdered curcumin diet.

Macroscopic lung metastasis, or metastasis that is visible to the naked eye, was seen in 96 percent of the mice in the control group. Treatment using Taxol alone only "modestly reduced" the incidence of metastases, while the group using curcumin alone and curcumin plus Taxol "significantly reduced" both the incidence and numbers of visible lung metastases.

Janet      Permalink

Oct 12, 2005

Comedian Louis Nye Dies of Lung Cancer

Comedian Louis Nye Dies of Lung CancerThe man who brought us the phrase "Hi Ho, Steverino" has died of lung cancer. Louis Nye died over the weekend of lung cancer at age 92.

Louis Nye is one of America's most popular actor and comedians. He came into prominence on the long running Steve Allen Show where his "HI-HO STEVERINO" became a household phrase. Daily Variety described him as,..... "One of the finest actor/comics who turns himself into many characters who are vastly entertaining."

Louis has appeared in every area of show business including radio, Broadway, movies with Jack Lemon, James Garner, Lucille Ball and Robert Mitchum..... The Lecture Circuit, Concerts, Night Clubs And Television. He has starred on TV with Judy Garland, Jack Benny, Bob Hope, Jimmy Durante, Jackie Gleason, Dolly Parton, Steve Martin, Bill Cosby, Jonathan Winters..... Appearances on Love Boat, as the memorable Sonny Drysdale on The Beverly Hillbillies, The Munsters, St. Elsewhere,.....the list goes on and on.

Janet      Permalink



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Cancer
Cancer is a very common disease, approximately one out of every two American men and one out of every three American women will have some type of cancer at some point during the course of their life. Cancer is more common in the elderly and 77 percent of cancers occur in people above age 55 or older. Cancer is also common in children. Cancer incidence is said to have two peaks once during early childhood and then during late years in life. No age period is completely exempted from development of cancers. Some cancers occur predominantly in the elderly, other types occur in children, Cancer occurs in all ethnic races, however the cancer rates and rates of specific cancer types may vary from group to group. Late stages of cancer may be incurable in most cases, but with the advancement of medicine, more and more cancers are becoming curable.

Medicineworld.org: Cancer blog

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